Sentence examples for modified binding and from inspiring English sources

Amplification products were separated from unused primers by using QIAquick 96 PCR purification cartridges (Qiagen, with modified binding and wash buffers).

QIAquick 96 PCR purification cartridges (Qiagen, Hilden, Germany, with modified binding and wash buffers) were used to remove unincorporated primers before tags were decoupled from amplification products by UV photolysis in a flow cell and analyzed in a quadrapole mass spectrometer by using positive-mode atmospheric pressure chemical ionization (APCI-MS, Agilent Technologies, Palo Alto, CA, USA).

This compound (VUF10166) shows modified binding and functional effects when tested on A+B− receptor containing mutant 5-HT3B subunindicatinganing allostericric effect at an A+B− interface, although it also competed for granisetron at the A+A- binding site.

We predict that the remaining probes, which have shorter, or no, accessible sequences, will exhibit modified binding behavior, and we plan to conduct experiments to characterize this behavior.

Soluble PtdIns(4,5 P2 and PtdIns 3,5 P2 also interact with the canonical PI binding site by the same assay, inducing large CSPs, especially in β7, that suggest a modified binding orientation and slightly higher affinity (supplementary Fig S6 online).

As a consequence, both increased expression of AP-1-dependent target genes by the activating transcription factors c Jun/c Fos and modified binding activity of the resulting AP-1 complexes via the action of deactivating JunB and JunD may contribute to the pathogenesis of RA.

Maleimide was then coupled to the modified binding site resulting in a decrease in biotin affinity.

Mutations in the protease flap region are recognized as critical for modified binding of a number of PIs.

Apart from the results predicted in this study, this model can also explain several cases from available literature on ubiquitin mutants with a modified binding profile.

The multiple convergent changes were presumably driven by the need for these coregulatory transcription factors to better recognize the newly modified binding sites.

Changes of epigenetic marks, such as DNA methylation, can affect the chromatin structure and modify binding of transcription factors and gene expression.