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For example, sites in cluster 2 generally carry H3K27me3-modified (a marker of transcriptional repression) nucleosomes on one allele and H3K4me3-modified (associated with transcriptionally active regions) nucleosomes on the other.
To produce such high frequencies, toothed whales possess modified tissues associated with the blowhole on the right side of the head; the left side is not modified, and the result is skull asymmetry.
Query: 'Find all modified proteins in a pathway' —this query enables users to retrieve modified proteins associated with Reactome pathway(s) of interest for further analysis.
εmethyl is the interaction energy between the DNA methyltransferase and the modified nucleosomes associated with the gene.
Recent methylome studies of brain tumors have disclosed a list of new epigenetically modified genes associated with gliomagenesis and different glioma clusters [ 2- 4].
High cholesterol levels in CIC are considered to be surrogate markers of modified LDL associated with increased carotid intima-media thickness and cardiovascular events.
The classification of Galeommatoidea is in a state of flux, mostly likely owing to their reduced, and sometimes highly modified, morphologies associated with symbiotic life.
The binding of hypersensitive DNase and the modified histones associated with active transcription may facilitate the high expression of H2H genes.
Additional analysis of the HCF1 peptides from this experiment revealed extensive O-GlcNAc modifications, indicating that HCF1 is heavily modified when associated with SETD1A.
The pathways with the most statistically significant level of enrichment and largest number of modified transcripts associated with arsenic exposure were those involved in defense and immune response (listed in Table 1).
The enrichment score of each group is measured by the geometric mean of the EASE Scores (modified Fisher Exact) associated with the enriched annotation terms that belong to this gene group.
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