Sentence examples for modified alignment from inspiring English sources
Thus, we tried a modified alignment score SL that penalizes sparsely distributed matches compared to locally enriched 'match blocks'.
The modified alignment was then used to generate a phylogenetic tree using Maximum Likelihood (Guindon et al., 2010).
AMTP sequences generated for this study (Additional file 4) were included in a modified alignment from [ 10] and phylogenetic analysis was performed as in [ 10].
Therefore, we investigated whether standard and the suggested modified alignment parameters will provide similar divergence estimates between the ancient and modern horse.
For this purpose, we analyzed test samples by aligning their microarray profiles against the annotated and normalized GeneSapiens microarray reference database and applied a slightly modified alignment of gene expression profiles (AGEP) method - weighted AGEP (wAGEP) - which we recently developed and described for classification of cell differentiation patterns [ 22].
The program noisy exports a Postscript file, visualizing the quality of the sites of the reordered input alignment (see Fig. 2), recording their reliability score as xy-data, and containing a modified alignment for further analysis in which sites with reliability q < q cutoff are removed.
All modified alignments were concatenated into a single data set for phylogeny estimation.
Gap penalties also modify alignment length and identity; increased gap penalties produce shorter higher identity alignments, whereas lower gap penalties produce longer lower identity alignments (Fig. 3).
However, the present study appears to be the first to report on an orthosis that can modify alignment in healthy elderly participants without spinal deformity or chronic LBP.
The multialignment of overlapping reads to each reference read is used to detect likely sequencing errors and modify alignments accordingly.
AEI was then calculated as the ratio of the reference allele count from the standard alignment versus the reference allele count at the switched alleles in the modified genome alignment.
