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While we have modified a prior OGA method [ 13] for scoring ambulatory canine myelopathy patients so that it might be of particular use to compare to IGA findings, an additional limitation is that our scoring system is not appropriate for non-ambulatory patients.
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Our questions about monitor removal were modified from a prior study's questionnaire [ 8], and we found no other study containing similar items.
RNA-seq libraries were prepared using a directional RNA-seq protocol modified from a prior published approach [ 49] and detailed in the Additional file 1: Supplemental experimental procedures, Directional whole transcriptome sequencing protocol.
The Consolidated Standards of Reporting Trials diagram and patients characteristics at baseline and at follow-up (modified from a prior publication 15) are included in this report for completeness (figure 1 and table 1).
The LCAR prior combines a discrete uniform distribution on this set of candidate structures with a modified CAR prior for the random effects, which combined with the Poisson likelihood completes a full Bayesian hierarchical model.
The TAO-Gen algorithm could work in these situations but would need to be modified to use a prior different than the uniform prior used in this case.
They increase understanding of participants' views of the intervention and trial processes, so that they can be modified prior to a large-scale trial.
Additionally, the effect of two translational enhancement motifs (the TMV omega element and a modified sequence directly prior the start codon) were analysed.
Furthermore, motifs responsible for enhancement of translation efficiency – such as the TMV omega element and a modified sequence directly prior the start codon – were tested in this model.
Repair of modified guanine prior to DNA replication is an essential feature for the maintenance of cell homeostasis because 8-oxo-dG is a mutagenic base that can result in GC→TA transversions.
Following a preliminary pilot with volunteer therapists, the questionnaire was modified slightly prior to conducting the full survey in November 2007.
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