Sentence examples for modifications with high from inspiring English sources

Custom-made zinc-finger nucleases (ZFNs) can induce targeted genome modifications with high efficiency in cell types including Drosophila, C. elegans, plants, and humans.

However, because the kinetic variation signals produced by mC modifications are very weak, PacBio sequencing is unable to detect mC modifications with high accuracy [66], [68].

Here we report the development of zygote electroporation of nuclease (ZEN) technology to generate mice carrying targeted genetic modifications with high efficiency.

S. pombe also shares many of the chromatin modifications with higher organisms.

H3.3 dissociation rates were found to differ greatly depending on post-translational modifications with higher dissociation rates associated with active marks and lower rates at heterochromatic marks.

The implementation of repeatable imaging techniques able to sensitively identify these modifications with higher specificity and mini-invasive sampling approaches able to safely provide comprehensive biological insights represent therefore essential tasks for the translational development of LN research in human disease.

The results confirmed the ability of the proposed method to estimate color modification with high accuracy.

Treatment of PIL consists of lifelong dietary modification with high protein and low fat substituted with MCT.

We found no evidence of mitochondrial oxidative protein modification with high fat feeding, indicating that ROS-mediated damage was unaltered.

[2a] Although various possible mechanisms have been proposed for PSSG, [1a] the delineation of its functional consequences in vivo remains a longstanding challenge owing to lack of appropriate tools to globally identify this important modification with high sensitivity.

These PBL-specific promoters were associated with the full complement of modifications associated with high expression, whereas the DMR associated promoters were not.