HCHO selectivity of the FeOx clusters in SBA-15 could be improved by the modification with either an acidic group (e.g., phosphate) or an alkali metal ion, which increased the dispersion or changed the local coordination environment of iron species.
Patients were therefore additionally randomized to receive bias modification with either a word- or face-based task.
Chromatin immunoprecipitation (ChIP) analysis was used to measure specific histone modifications associated with either active transcription (methyl-K4, acetyl-K9, and acetyl-K14 of histone H3) or silenced transcription (dimethyl-K9 of histone H3) at the PTRE-HPRT promoter (Fig. 5).
Genome-wide transcriptional activity of the individual cell populations was assessed by RNA sequencing and the distribution of histone modifications associated with either active or repressed regulatory elements was investigated by ChIP sequencing.
Even though the change of expression experienced by the different breast cell lines is only observed for one of the two markers analysed, we cannot disregard the fact that the modification correlates with either loss of epithelial phenotype or increased invasiveness, which are all markers of cancer progression.
To determine whether any of the histone modifications selectively associates with either allele, we again searched for informative sequence SNPs at the IGF2BP1 promoter region in the CEPH pedigree.
Further experiments using immunofluorescence to localize the positions of histone modifications typically associated with either active or inactive chromatin confirmed that these two types of chromatin tend to occupy distinct parts of the nucleus, with inactive chromatin mostly near the periphery and around nucleoli, and active chromatin located more internally (e.g., [ 60, 61]).
Chemical, enzymic, and physical modification of starch, with either preservation or destruction of the native granule, broaden the functionality-imparting properties of different starches.
The lower level of observable CUL3Δ403 459 may also be due to non-proteolytic hyper-modification of CUL3Δ403 459 with either Nedd8 or ubiquitin.
Modification of ODN2006 with either organic molecules at the 3'-end or oligonucleotides at the 3'- or 5'-ends enhanced the stimulatory activity.
