Sentence examples for modifications with age from inspiring English sources
Indeed, whilst the age-associated hypomethylation of the Avp had no effect on mRNA expression levels, Hnf4a repression by histone modifications with age resulted in lower levels of expression.
The modifications with aging in the secretome of the different cell types present at different phases of regeneration is probably then crucial, as is expression of relevant cell surface receptors, which can also change with age (e.g. IGF and IGF receptors).
The following statement is the basic premise of the proposed modification: with age identification, the significance of the error depends on the absolute age value.
Densitometric analysis of 3-NT modified CKm 130 reveals a progressive increase in 3-NT modification with age.
The main explanatory variable showed effect modification with age, mortality and the composite of hospital status and municipality population size.
Specifically, although most miRNAs are loaded into Ago1-RISC and remain unmodified, a subset are loaded into Ago2-RISC and become 2′- O-methylated and protected from Nibbler modification with age.
However, only two age groups: young and middle-aged pigs were used in our study, and examining pigs of additional consecutive ages is necessary to further elucidate the changes in epigenetic modifications associated with age, as well as the ultimately complicated mechanisms underlying the aging process.
Epigenetic modifications on DNA and histones change with age and vary in different cell types, disease states (e.g., cancers), and developmental and differentiating stages [ 27].
The modifications observed with aging have also been related to a progressive impairment in cognitive performance [ 5].
The number of histone modifications associated with aging was larger than those associated with post-mating changes, especially for H3K4me3 (Table 1).
They were followed up with an interval of 5 years in order to study and evaluate physiologic and pathologic modifications connected with aging.
