However, transfection efficiency of mRNA has been greatly improved [5,6] and the half-life of mRNA has been dramatically increased, ranging from a few minutes to several hours by chemical modifications [7-9], which facilitates the use of mRNA for therapeutic gene transfer.
Recently, a number of precision genome engineering techniques have been developed which facilitate modification of genes / genomic regions directly in the organism of interest without the need for isolating the genes/genomic regions.
SEM allows for constructing and validating measurement models and provides multiple model fit statistics and modification indices, which facilitates item reduction and evaluation and comparison of the original and shortened APQ.
Several other genes containing MYST, SET, and CHROMO, and BROMO domains, which facilitate or recognize specific histone modifications, were also identified.
In addition to playing possible roles in SUMO modification, SIMs may also act as protein interaction modules which facilitate the formation of multi-protein complexes.
A comparison between modified and unmodified HZSM-5 reveals the appearance of cavities and cages which facilitate the alkylation reaction and shape selectivity of the catalyst after modification.
We have cellphones, which facilitate last-minute get-togethers.
which facilitate traffic.
At the same time, it identified some proteins having both these modifications, which would facilitate the future evaluation of cross-talk between these two vital PTMs.
Many of the RITE cassettes contain unique restriction sites between the different elements, which facilitates modification of the constructs for other applications.
