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It is possible that these chemical modifications are recognized by plant receptors with subsequent activation of the second transcriptome-switch.
Much therefore remains to be learned regarding the activating roles of posttranslational modifications in HSF1 regulation, their role in stress mediated transcription and the mechanisms by which such modifications are recognized by regulatory pathways in cells and converted into altered function.
The various types of ubiquitin modifications are recognized by different downstream effectors in the cell and trigger distinct functional outcomes (for reviews, see [ 11, 12]).
Upon DNA damage, p53 undergoes dimethylation at Lys382 (p53K382me2), and this posttranslational modification is recognized by 53BP1.
This modification is recognized by the mannose 6-phosphate receptor in the trans-Golgi network, which captures these proteins and transports them to late endosomes.
However, these observations are somewhat akin to those reported in yeast where the H3K4me2 modification is recognized by the Set3 complex that deacetylates histones in 5' transcribed regions [ 13].
A possible solution to the problem of aligning termini to be included in this analysis would be to assume that the respective motifs for posttranslational modifications are recognized as extended peptides followed by some linkers of varying length.
Biallelic events were recognized by either transmission of modified loci to >50% of progeny or modification of two discernable chromosomes (e.g., the vasa-Cas9 and balancer chromosomes).
Six were recognized by the anti-Vβ8.1,8.2 anti-Vβ8.1,8.2
Histones bearing H4KC16ac were recognized by an H4K16ac-specific antibody, and the PTM-analogue caused chromatin decompaction, which is a hallmark of this modification.
Lifelong treatment adherence and lifestyle modification are recognized as the most critical components of diabetes management.
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