Sentence examples for modifications were present from inspiring English sources
Whole-genome sequencing confirmed that no off-target modifications were present in the mutants.
Therefore ChIP assays were next conducted to determine whether a subset of histone modifications were present within the nucleosomes at these regions.
We performed chromatin immunoprecipitation (ChIP), to determine which promoter-associated modifications were present in the gene ORF in rco1Δ mutants using primers tiling the STE11 locus (Figure 2B F).
No such morphological modifications were present in LGI1−/− pups at postnatal day 8 before seizure onset, or in LGI1+/− and wild-type animals.
Finally, as a negative control, we monitored all four modifications at a site beyond the end of each gene and found none of these modifications were present there.
Next, we checked whether these distinct chromatin modifications were present in the undifferentiated iPSCs, and we detected no obvious differences between the undifferentiated iPSCs and ESCs (Supplementary Figure 6, and data not shown).
Modal meta-models are used to approximate modal properties of structures when structural modifications are present.
We have recently shown that the glycosylation of extracellular matrix proteoglycans is modified in leiomyoma: increased amounts of galactosaminoglycans with structural modifications are present.
Thus, we show that novel post-translational modifications are present in hepatic mitochondrial, nuclear, cytoplasmic, and microsomal compartments and ethanol ingestion, and its associated metabolism, induce specific changes in these acyl modifications.
Using a bottom-up strategy effectively destroys information on how those individual chemical modifications are related, meaning researchers may be able to see that given modifications are present, but are largely blind to their interplay and stoichiometry.
Because most modifications are present in low stoichiometry and would typically be discriminated by MS detection, a prerequisite of examining any modification on a global scale is the development of highly efficient enrichment strategies prior to MS measurements.
