Sentence examples for modifications were enriched from inspiring English sources

The identified chromatin modifications were enriched during apoptosis and were present in circulating chromatin in SLE patients.

Regions associated with a variety of states implicated in gene activation as identified by histone modifications were enriched for trait-associated SNPs.

Proteins that are regulated by such modifications were enriched in both lists of proteins, those affected by Ethe1 deficiency as well as those co-expressed with Ethe1.

In HepG2 cells, active and repressive histone modifications were enriched to comparable extents at the DLK1 promoter and the MEG3 DMR.

However, a recent analysis of published human epigenomic data found that 10 histone modifications were enriched in the 5' introns of human genes independently of the level of nucleosome occupancy [ 12].

When the long-range repressing group 1 was compared to the non-repressing group 3 most of the active histone modifications were enriched in group 1.

Thus, specific histone modifications are enriched in regions with DNAm changes during long-term culture.

These modifications are enriched at the 5′ ends of genes [ 41].

Reflected in ChIP-Seq data, the signals of these histone modifications are enriched over large regions, but lack well-defined peaks.

Applying ChIP on ChIPtechnology, Carrell also found that in human sperm histone modifications are enriched in Hox developmental genes, which may be very important for early embryonic development [ 15], further confirming the importance of histone modifications for the early development.

In mouse spermatocytes, both these modifications are enriched on the XY body in late prophase nuclei (late pachytene-diplotene) and persist on the sex chromosomes in round spermatids [ 66, 58].