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Other modifications to the guidelines are more worrisome.
Other minor modifications to the Guidelines and interpretation of Schema categories were made during the formal annotation phase, whether raised by one or both annotators; these were again resolved by discussion, with final resolution left to the curator.
The second stage instrument (B) also encourages clinicians to reflect on contextual issues particular to the management of hypertension in general practice, and allows them to suggest potential modifications to the guidelines.
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Developers may choose to make modifications to the guideline document before it is finalized and disseminated.
In all, 100 patients were recruited in phase 1 and 2 (as with modification to the guidelines, it was felt appropriate to include a large number of patients at this stage) and 50 patients in phase 3.
The CONSORT and Practihc groups describe modifications to the CONSORT guidelines to help readers assess the applicability of the results Randomised controlled trials are used to assess the benefits and harms of interventions in health care.
Since then, there have been many local modifications to the original guideline as a result of developments in anaesthetic practice and changing patient population.
The remaining four extracts were prepared as MID-tagged libraries with the same (as above) modifications to the manufacturer's guidelines.
We review earlier guidelines on the information that is necessary from preclinical studies before a compound enters clinical trials, and propose modifications to these guidelines.
Similarly, modifications to the intra-operative technique guidelines of the Orthopaedic Competence Assessment Project and the addition of a tailed OSATS scale were applied to assess diagnostic knee arthroscopy [ 13, 55].
For example, the recent modification to the American Thoracic Society guidelines for the treatment of hospital-acquired pneumonia [ 10] considered contemporary resistance data.
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