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Further modifications to the alignment were done manually.
The alignment found by the program was compared to structural overlays of sex-lethal and FIR1+2, and, accordingly, slight modifications to the alignment were manually performed in the region linking the two RRM domains to reflect the true structural alignment of those residues.
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We describe the profile alignment algorithm with core constraint in terms of required modifications to the canonical algorithm for local alignment (Smith and Waterman, 1981).
However, it suffers from relatively low production rates and poor control of fiber alignment without substantial modifications to the fiber collector mechanism.
Interestingly, this was achieved without any modifications to the search algorithm itself, since the score dissection was applied to the alignments post mortem.
Manual inspection of the alignment differences (resulting, for example, from different tools, changed parameters or modifications to the reference MSA) is supported via a differencing function.
The modifications to the bank agreement had been expected.
Every new iteration has brought small modifications to the space.
Work also started on modifications to The Other Place.
Code-Level Modifications to the G2.
At this time, the highway had the same extent as it does today; the only changes made to the highway over the years were slight modifications to its alignment due to the straightening of connecting highways.
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