By further modification through addition of a palmitate at its N terminus, the mature signaling molecule Hh-N is generated.
In contrast, settlement, which occurred over an extended reproductive period (June Sept), appeared insensitive to substrate modification through additions of rock or shell (Expt 1 3).
Lysine residues on histone tails may also undergo another form of covalent modification through the addition of an acetyl functional group.
To increase its time of permanence in the tissue, a chemical process called "crosslink" is performed, whereby an artificial modification through the addition of chemicals alters its physical and mechanical properties.
Post-translational modification of PML through addition of SUMOs is pivotal for the formation of PML nuclear bodies [ 22, 23], and many proteins found in the PML nuclear bodies are SUMOylated [ 24, 25].
Reversible post-translational modifications (PTMs) of proteins through addition and removal of molecular moieties are essential in exerting rapid changes to external stimuli without the input of transcription, protein synthesis, and subsequent turnover of messenger RNA and protein.
The adaptation process that maintains receptor sensitivity is mediated by the covalent modification of the chemoreceptors through addition and subtraction of methyl groups by the enzymes CheR and CheB, respectively.
The evolution of the family came through modifications or additions of the core stages and addition of strap-on solid rocket motors to increase lifting capacity.
This involved the development by two independent analysts of an initial coding framework capturing the overarching and related sub-themes within the local language transcript, which was then synthesised through discussion with modification or addition of codes until theoretical saturation was obtained.
In addition to hydrophilic treatments, studies also suggest the application of chlorinated plasmas for hydrophobic modifications through the deposition of polymerized chlorinated films or hydrogen atom replacement (Hubert et al. 2013).
This modification occurs through the addition of mono-methylol (-CH2OH) groups to RNA, as well as formation of secondary modifications such as methylene bridging, preferentially at adenine residues [ 8].
