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Our data suggest that once it is retrotranslocated to the cytosol, Nrf1 is not only deglycosylated and proteolytically cleaved after Trp103, but it also gains one or more additional modifications, the nature of which remains unknown.
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Sulfate modification affected the nature of interaction of CrO x species with the SBA-15 support.
The higher selectivity to ethylene has been related to the modification of the nature of Ni O species, which implies a lower production of carbon oxides.
In this case, especially near plasmon resonances, strongly overlapping evanescent fields exist, leading to significant modification in the nature of the resonance.
Consequently, by following the arguments close to the one in [17] with necessary modification required the nature of our problem, we establish a general decay result which includes the usual exponential and polynomial decay rates.
The protocol developed was based largely on Kerk et al. [ 51] and the main modification was the nature of the embedding material.
Nonetheless, the introduced epigenetic modification might not be stable in all genomic contexts and will depend on the pre-existence of other activating or repressive epigenetic marks, the location of the locus in the euchromatic or heterochromatic region, as well as on the extent of the introduced modification and the nature of the mark itself.
This is done by applying the idea presented in [23] with some necessary modification due to the nature of the problem treated here.
Functionalization of vancomycin at either the V3 or the X1 position decreased monomeric activity by 6−75-fold depending on the modification site and the nature of the adduct (P < 0.08 for all comparisons).
It will often (though perhaps not always) be possible to make explicit the elements open to modification, and stipulate the nature of the facilitation process through which this will occur.
The Casey Martin issue turned on provisions of the disabilities act requiring those operating public facilities such as golf courses to make "reasonable modifications" for people with disabilities unless those modifications would "fundamentally alter the nature" of the activity.
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