Sentence examples for modifications the functional from inspiring English sources

Likewise, although enhancers are strongly associated with characteristic histone modifications, the functional significance of such modifications remains unclear, and the mere presence of an enhancer-like signature does not necessarily indicate that a sequence serves a specific function (71, 72).

Since stem cell fate is not solely determined by epigenetic modifications, the functional consequence of the potential ability of PL to induce either cardiovascular or mesodermal transdifferentiation will eventually depend on the tissue microenvironment surrounding the ADMSCs.

With minor modification, the functional screening methodology reported in the present study may be extended to isolate plant genes that confer tolerance to a diverse array of possible abiotic stresses.

In previous studies, we had found that similar modifications do not change the functional properties of PC-1 in a series of in vitro functional assays conducted on over-expressed protein [13], [19] and unpublished.

The results of proximate analysis and characterization show that the oxalic acid modification affected the biosorbents content, surface modifications and the functional groups present.

Zhou, V. W., Goren, A. & Bernstein, B. E. Charting histone modifications and the functional organization of mammalian genomes.

FTIR analyses were carried out on the dried samples to find out modifications in the functional groups after adsorption process.

These structural changes correspond to the modifications in the functional organization and in the resulting behaviors.

These covalent modifications define the functional state of chromatin via both cis and trans mechanisms.

Glycosylation is the last of the modifications and the functional glycosyltransferases for vancomycin biosynthesis have been well-characterized biochemically [ 10, 15].

Thus, the location of intragenic histone modifications and the functional roles associated with different localization patterns remain areas of intense investigation.