Sentence examples for modifications that target from inspiring English sources

Thus, if queries or modifications that target specific records can be observed, encrypted B-Trees can only provide security guarantees against Q&NBK-attackers that have no background knowledge.

Possibly, CCR3 undergoes post-translational modifications that target it toward the nucleus normally.

However, non-canonical ubiquitin-based post-translational modifications that target proteins for proteasomal degradation have been described as well.

To learn how geminin overexpression prematurely releases TopoIIα from chromosomes, we looked for modifications that target and/or release TopoIIα from chromosomes.

The discovery of nuclear histone acetyltransferases (HATs) in the mid nineties has literally opened a new field of investigation into post-translational modifications that target histones and modulate the chromatin state either locally or over large genomic loci.

Molecular dynamic simulations and energetic analyses suggested a direct role for CRAM-1 in disrupting proteostatic clearance of misfolded and aggregated proteins, by forming stable complexes with (poly)ubiqui-tin modifications that target dysfunctional proteins for degradation.

One mechanism to control protein localization is palmitoylation, a protein-lipid modification that targets cytosolic proteins to specific membranes (Fukata and Fukata, 2010; Thomas and Huganir, 2013).

Moreover, the addition of F2,6BP to total cell lysates was found to increase the cyclin-dependent kinase (Cdk -dependent phosphorylation of its substrate p27 at threonine 187 (T187), a posttranslational modifiCdk -dependentrgets phosphorylationtiof (its. high Cdk activity substrates p27 levels).

Signaling cascade intermediates are subject to post-translational modifications that influence target protein activity, localization, and function, such as protein phosphorylation, mediated by the opposing function of protein kinases and phosphatases (Shi 2009).

On the bright side, intensive behavior modification programs that target weight loss at the time of diagnosis (of prediabetes), the CDC says, have demonstrated the ability to significantly reduce its progression into Type-2 Diabetes.

The IPA-identified network for genes regulated by Hcy revealed strong interactions of those genes with the ubiquitin C (UBC) posttranslational modification system that targets proteins for proteolytic degradation (Fig.  6).