Sentence examples for modifications that may affect from inspiring English sources

There are also other modifications that may affect the activity of splicing factors such as sumoylation [48], and arginine methylation [49], [50]; however further studies are needed to reveal whether they play any role in ccRCC pathology.

A second caveat is that the RT-qPCR method used in this study would not account for post-translational modifications that may affect secretion, function or half-life of the antimicrobial peptides.

The methodology presented herein not only allows for a prolonged monitoring of metabolic changes subsequent to transfection till the achievement of maximum protein activity, it also facilitates the time- and cost-efficient assessment of SNPs and other mutation/deletion associated protein modifications that may affect protein activity, stability or its intracellular localisation.

The involvement of modifications at post-translational levels that may affect differently the functionality of the LOX-1 isoforms encoded by the different Lpx-B1 genes and allele cannot also be excluded.

Cdc13p undergoes cell cycle phase-specific post-translational modifications, including phosphorylation and SUMOylation that may affect capping (Tseng et al. 2006; Li et al. 2009; Hang et al. 2011).

Epigenetic modifications are reversible modifications on the DNA of one cell or histones that may affect gene expression without altering the DNA sequence [ 100].

Epigenetic modifications are changes that do not alter the primary DNA sequence itself and include DNA methylation, histone modifications, and other changes in chromatin structure that may affect the regulation of gene expression [ 24, 39, 40].

The effects of alcohol on sperm DNA methylation need further exploration, as do other epigenetic mechanisms, including histone modification and the transmission of RNA species that may affect gene expression in the gametes and early zygote.

This post-translational modification event may decrease functional NDRG1 in prostate cancer cells that may affect its metastasis suppressor role.

In some cases, these modifications still allow the gene to produce a functional protein but with slight variations that may affect its function.

The difference observed between the fertilization capacity of the GM C57BL/6 lines (Figure 3a, Table 1) and inbred C57BL/6J mice (Figure 1a, Figure 2) is likely due to genetic modifications that may have affected fertility and the presence of alleles from other strains in lines that were not fully congenic.