In conclusion, modifications that increase the uptake of α-crystallin proteins into cells, without destroying their chaperone-like activity and anti-apoptotic functions, create the potential to use these proteins therapeutically.
Chemical modifications that increase the hybridization affinity of oligonucleotides are reasoned to confer higher potency, i.e., modified oligonucleotides can be dosed at lower concentrations to achieve the same effect.
The DoD estimates that there will be 8 million smartphones in service over the next three years, and most devices used to handle classified data have been subjected to pricey modifications that increase their final cost up to four times.
This region is necessary for expression of the gene and is affected by epigenetic modifications that increase the chromatin accessibility specifically in endothelial cells.
In response to DNA damage, p53 undergoes a number of posttranslational modifications that increase its stability and transcriptional activity.
Dietary modifications that increase the intake of vegetables, fruit, and grains and decrease the intake of saturated fats and refined sugars are recommended.
In the present study, we examined the hypothesis that the adventitious roots produced in tamarack in response to flooding are able to maintain high hydraulic conductivity by developing structural and functional modifications that increase the apoplastic bypass.
Specifically, the scaffold nucleoporins Nup107-Nup160 of NPCs persist for the entire lifespan of post-mitotic cells and are vulnerable to oxidative modifications that increase nuclear permeability during aging (D'Angelo et al., 2009).
Therefore, the protection afforded by HMW tropomyosins may be a result of increased expression and posttranslational modification that increases their association with the hypoxic actin cytoskeleton.
The IC-modification that increases the SDO, QO, and IFCCO or decreases the SDFe can make the catalyst more powerful.
