Exact(1)
It has been estimated that a cancer proteome may include more than 1.5 million proteins due to the wide variety of posttranslational processing and modifications that are possible.
Similar(59)
Therefore, a more likely possibility is that residual FACT from the initial trophozoite-like stage is sufficient for any possible chromatin modifications that are needed for transcription of gametocyte-specific genes.
It is difficult to say whether these differences reflect physiological effects relating to the expression of the protein product or possible protein modifications that were not identified in this study.
In October, New Jersey's Office of Legislative Services, a nonpartisan research body, issued a legal opinion that retirees may not be stripped of their health benefits, but that "reasonable modifications" are possible.
The authors concluded that proteomics has potential to study the air space in patient's with ALI/ARDS with the ability to identify post-translational modifications that would not be possible with other techniques.
These results demonstrate that 5′ chemical modifications of the crRNA are possible without damaging the activity, if the 5′ end of the crRNA is extended.
Given the recent characterization of radical SAM enzymes involved in sugar modifications, it is possible that AviX12 may exhibit similarities to BtrN or DesII (sections 8.2 and 10.3).
Given the precedent of interplay between serine/threonine phosphorylation and O-GlcNAc modifications, it was possible that elevated O-GlcNAc interference with specific PKA phosphorylation signaling events contributed mechanistically to 9d inhibition of forskolin-induced axon branching.
Kahn and colleagues [ 54] concluded that many of the noises causing sound peaks over 80 dBA were amenable to behaviour modification and that it was possible to reduce the noise levels in an ICU setting significantly through a comprehensive educational program of behaviour modification towards all the ICU staff.
He believed that only small modifications would be possible over lifetime.
As proven, effective and safe preventive and abortive therapies for migraine are available in adults, it would be inappropriate and possibly unethical to conduct the double-blind, placebo-controlled studies necessary in young migraineurs to prove that disease modification is possible in migraine when optimally treated early in its course.
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