It was recognized early on in the field that, in addition to regulating protein function by coordination to metal-based prosthetic groups, NO could covalently modify protein cysteines, a modification subsequently termed S-nitrosylation.
After independence on January 1 , 1960 the flag was retained, but slight modifications were subsequently made.
Finally, in some ligand classes the biological response or target specificity can vary significantly upon very slight chemical modifications, and subsequently, minor topological modifications.
When the effect of genome modifications is subsequently screened at the molecular level, usually a large number of mRNA and protein changes are observed [6] [8].
Most cases of key innovation such as feathers in birds [10], the turtle carapace [2], [3], and the snapping claw in alpheid shrimps [11], involve extreme morphological modifications that subsequently improve performance capacity [12].
The injury begins inducing molecular modifications that subsequently evolve into cellular damage.
These modifications will subsequently be presented to the graphic artist and a second draft will be procured.
Modifications were subsequently made to the instrument leading to the current revised version, which has been identified as a widely used PRO measure for CF [ 15– 17].
Sickle haemoglobin (HbS) polymerises when deoxygenated, resulting in red cell membrane rigidity and surface protein modifications that subsequently contribute to vaso-occlusion.
Previously, a pilot survey was applied to 10 patients at the University's Dental Clinics, and minor modifications were subsequently made to the questionnaire.
