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Functionalization of chitosan structure through various chemical modifications provides a solution to these limitations.
A partially peptidomimetic helicokinin analogue, containing two structural modifications provides a deeper insight into the structural-requirements for receptor-binding.
The ability to breed pigs with multiple genetic modifications provides a unique opportunity to explore the immunologic challenges of pulmonary xenotransplantation.
Immunolocalization allows discrimination between the range of modifications, provides a genome-wide level of analysis, allows differential assessment of nuclear localisation, and is compatible with the limited DNA available within the early embryo.
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Mesophyll modifications provide a means of storing water.
Our data show cell-type-specific patterns of DNA and histone modifications provide a modulatory layer by determining accessibility of genes to regulation by TGF-β/SMAD3.
A number of modifications of the stem occur in angiosperms, and many of these modifications provide a means for herbs to become dormant and survive for a period of years.
Histone modifications provide a dynamic and versatile code for the recruitment of factors that control gene transcription [43].
Furthermore, in vitro analysis of myocyte calcium handling, contractile kinetics, and biochemical analysis of protein post-translational modifications provide a sub-cellular perspective into a molecular and cellular basis for pathologies observed in vivo.
This study is a demonstration of the sensitivity of SERS-based COIN agents and their utility for detecting proteins and protein modifications, providing a roadmap for more flexibly to add new parameters in simultaneous measurement of biological events in single cells.
Post-translational modifications provide a mechanism for regulating protein structure and function.
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