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In addition, some polymers require chemical modifications, owing to their lack of sites for cell adhesion and frequent immune responses, triggered by their byproducts [29].
The prevalence of dose modifications owing to DRAEs (Supplementary Figure 1) was generally consistent with the prevalence data for DRAEs.
In the oldest patients, the prevalence of dose modifications owing to DRAEs tended to be higher than in younger patients; however, the relatively small number of patients in the oldest group after month 12 precludes meaningful conclusions.
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It is either used for encapsulation or surface modification owing to its targeting capabilities and avoiding uptake by reticuloendothelial system.
In each age group, most patients (>50%) did not require any dose modification owing to AEs; the proportion of patients requiring two or more dose modifications was low (20 23% Figure 2A).
In this study, no effect modification by Hp status at baseline was observed, either because there is no such modification or owing to the fact that a large percentage of cases and controls were Hp positive.
Construction of multiple BAC-based HACs demands the development of novel BAC modification methodologies, owing to the difficulties inherent in the manipulation of high-molecular weight DNAs by traditional subcloning techniques [ 23].
We evaluated menopausal status as a potential effect modifier but were unable to evaluate effect modification by race owing to small numbers.
Furthermore, we found that the reduced modification rates were mainly owing to the decrease of A modification, implying that HBV infection can repress the mechanisms responsible for the A modification without affecting the other modifications.
Conductive ceramics, advanced industrial materials that, owing to modifications in their structure, serve as electrical conductors.
Other major modifications were recently made owing to a few map representation differences, which affect the entire matching process.
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