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There are also multiple reported post-translational parkin modifications outside of the Ubl domain, including S-nitrosylation [ 128, 129] and NEDDylation [ 130], which have been reviewed recently [ 123].
These animals did display altered CORT responses to an acute episode of restraint stress following the chronic stressor, suggesting that epigenetic modifications outside of the central nervous system may have functional relevance.
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The relatively low frequency of genetic modifications outside the futA and futB loci supported our hypothesis of homologous recombination events taking place at a high frequency between the two paralogous α1,3-FucTs.
What's more, over two-thirds of modifications occur outside of the program.
These results suggest that the serological differences between the members of these seven groups have been generated by acquisition of modification genes outside of the O-AGC as shown for O17 and O44 of Gp9.
The cement can make a mess, so it's preferable to perform this modification outside or over top of a piece of paper.
Therefore, while there are certainly limitations that need to be considered when a reactive metabolite is added exogenously to a cell rather than generated intracellularly, for certain reactive metabolites the profiles of modification outside and inside a cell may be similar.
Active site modifications of proteins by HNE would theoretically have a greater impact on protein function relative to modifications that occur outside of the active site.
The administration says that HAMP deserves some credit for "proprietary" modifications that happen outside of the program.
Dose modification outside the standard dose requirements while occurring infrequently 50-700% of the pediatric caregivers modified dosages in only '1-20'1-20%atients') reflects individual patient factors.
Ex vivo gene therapy involves the genetic modification of cells outside of the body to produce therapeutic factors and their subsequent transplantation back into patients.
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