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Extending the method to other histone and non-histone proteins ought to reveal several new associations between enzymes and modifications otherwise considered distinct.
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Notably, some epidemiology textbooks [ 5] reserve the term effect modification for when the modification is linked to a causal mechanism and use the reduced term modification otherwise.
The CEC system, in combination with other techniques, can potentially realize chromosomal modifications that otherwise cannot be achieved such as monosomies, complex abnormalities, and UPDs.
The combinatorial presence of different acetylations, methylations, phosphorylations, ubiquitylations and sumoylations of the different core histones constitutes the so-called histone code [ 17], which provides a specific binding platform for regulatory proteins that may also mediate the addition or removal of such posttranslational modifications, or otherwise affect chromatin accessibility.
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The law exempts foods if the genetic modification could otherwise be achieved via conventional breeding or found in nature.
It is very tempting to speculate that binding of the large number of FtsZ-interacting proteins to this tail might be regulated by post-translational modification as otherwise it is difficult to explain how so many different proteins may work in concert while binding to exactly the same FtsZ motif.
And again Hazlitt steps back and points out how Shakespeare set one character off against the other and presented characters of similar types but with slight modifications of their otherwise similar traits to convey a certain impression about human nature.
Otherwise, modifications such as cutting connector plugs from either fan or light will be required.
Bentley said in a statement that "Mulliner's sphere of operation extends from one tiny modification to an otherwise standard car, such as the embroidery of the owner's initials in the upholstery, to the design, commission and execution of a new state limousine for Her Majesty, The Queen".
One may also argue that lowering the admission age has the second advantage of offering a time window for benefits from lifestyle modification with an otherwise still expectant policy.
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