Sentence examples for modifications or protein from inspiring English sources

However, it is not known if any of these enzymatic modifications or protein interactions liberates P-TEFb directly from the 7SK snRNP.

Additional mechanisms might act in cells that cooperate with PIP2 or offer alternative regulation, including posttranslational modifications or protein cofactors.

Although lncRNAs may require post-transcriptional modifications or protein interactions to function, because the mature product is the functional end-product, measurement of its expression directly represents the levels of the active molecule.

Therefore, and although most of the attention when analyzing protein expression in plants has been directed towards protein accumulation, protein activity may play a bigger role in the final analysis, especially when compartmentalization results in protein with low or no activity, which in many cases is due to a lack of post-translational modifications or protein truncation [ 29].

Modifications can be grouped according to their stability or transience (reversible versus irreversible): irreversible types (such as irreversible redox modifications or protein deamidation) are often associated with aging or tissue injury, whereas transient modifications are associated with signal propagation and regulation.

We conclude that this experiment rules out all but post-translational mechanisms, such as changes in post-translational modifications or protein-protein interactions in regulating which genes c-Myb associates with during different phases of the cell cycle.

Alternatively, it could be that the increased activity of GADD45G induces rapid suppression of OCT4, SOX2 and NANOG function via for example disrupting posttranslational modifications or protein-protein interaction required for sustaining the self-renewal circuitry.

This suggests either that the purification process itself renders the protein inactive, or that the laboratory processes involved did not permit key post-translational modifications or protein-folding mechanisms [ 64].

We propose that PFT is regulated in planta, perhaps by post-translational modifications or protein-protein interactions, to reduce recognition and farnesylation of CaaX substrates with leucine in the terminal position.

Additionally, the correlation between mRNAs and protein levels are remarkably low and fail to provide indications about post translational modifications or protein-protein interaction that are believed to have significant regulatory effect on defense responses [ 22].

Additional mechanisms, potentially involving trans-factors, noncoding RNAs, other histone modifications, or proteins that remain bound to DNA through its replication, could encode the robust positive feedback required to enforce epigenetic inheritance of active or repressed states [ 1].