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By integrating in-host genoma, it induces modifications on cellular cycle proteins.
Such models will facilitate the evaluation of the impact of genetic modifications on cellular physiology and guide subsequent rounds of modifications to attain the goals of metabolic engineering.
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Channeling N-glycans to a uniform glycoform thus requires not only information on protein localization, but also a better understanding of the effect of glycan modification on cellular homeostasis.
Elucidation of amino acid sites of modification by HNE is critical to determining the effect the modification has on cellular signaling pathways.
Since, nitrotyrosination in plant cell has not been investigated, the aim of our study was to reconstruct the spatial structure of nitrotyrosinated plant α-tubulin with following modeling of possible mechanisms of this posttranslational modification influence on cellular processes.
While this approach is applicable to any tyrosine phosphorylated protein target, similar approaches could also be tailored for other domains recognizing post-translational modification sites on cellular proteins [ 55].
Specifically, the effect of PAMAM generation, surface charge and surface modification on toxicity, cellular uptake and transepithelial transport is discussed.
The aim of this study was to examine the impact of nanozeolite surface modification on its cellular uptake, retention inside the cell, and cytotoxicity in vitro.
The effects of these modifications on the chromatin and on cellular processes are very diverse, and a modification of the same residue can even have opposite effects depending on the type of modification.
The aim of the present study was to evaluate the effect of orange juice on cellular modifications induced by a fatty meal.
Detection of these modifications on a set of cellular proteins playing a well-understood role in cell biology can provide a broad snapshot of intracellular signalling.
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