Sentence examples for modifications of which from inspiring English sources

The Home Affordable Modification Program was initially supposed to help three to four million homeowners, but only 1.2 million received permanent modifications, of which about 27 percent have defaulted again.

Epigenetic mechanisms principally include DNA methylation and a variety of histone modifications, of which the best characterized is acetylation.

In terms of diversity, the data set included 23 noncanonical amino acid modifications, of which 11 were backbone N-methylations, 28 were natural amino acid substitutions, and 12 were deletions.

Only 131 genes (0.6% of total) were differentially expressed in both modifications of which 47 (0.2%) were more than two fold up- or down-regulated in at least one of the modifications.

One of the underlying reasons for the success of these folds in acquiring new functions is that they hold a wide active site that can accommodate complex and multiple substrates simultaneously and the presence of many surrounding loops, modifications of which can alter the chemical and catalytic properties of the protein, its substrate/product profile, or cofactor-binding properties.

On the one hand, it involves genetic modification, of which many of them disapprove.

The key to the development of such viruses is the identification of viral genes, the deletion or modification of which enables tumor-specific cell destruction.

This correlation serves to infer which factors, i. e., major axes of transcriptome variation, contribute to the modification of which phenotypes.

Furthermore, PTM sites are often located within short peptide motifs, modification of which influences the affinity for interaction with diverse binding partners (see section 3.1).

Intracellular lipofuscin accumulation may have important effects on autophagy the modification of which could form the basis for future novel glaucoma treatments.

In response to DNA damage, Sirt1 binds and deacetylates the p53 protein with specificity for its C-terminal Lys382 residue, modification of which has been implicated in the activation of p53 as a transcription factor.