Sentence examples for modifications of tumor from inspiring English sources

New-generation melanoma vaccines, which are based on genetic modifications of tumor cells to express cytokines, generated long-lasting systemic anti-tumor immunity in animal models.

Viral modifications of tumor cells were evaluated for their ability to induce a protective tumor response in model systems of rat fibrosarcoma, liver metastatic rat tumor cells, lymphoid tumor cells and hamster tumor cells.

Moreover, expression and post-translational modification of tumor biomarker proteins, which ultimately play a key biological role in neoplastic cells, cannot be revealed by nucleic acid-based technologies.

Various methods for "xenogenization" (modification of tumor cells) were suggested: induction of new foreign antigens, treatment with either chemicals or enzymes and use of mutagens.

Accordingly, identification of the physiological roles of nuclear Ptc-ICD7 fragments in the regulation of gene transcription and modification of tumor suppression should be future prospects.

The hypoxia-induced synthesis of HIF-1 α causes modification of tumor microenvironment.

Activation of mARs eventually leads to modification of tumor cell proliferation, migration and apoptosis [ 5, 6, 13, 14, 19].

Several potential functions for CTGF in tumor development in the group A tumors involve both direct action on the tumor cells and modification of tumor microenvironment.

In vivo modification of tumor cells will be beneficial for the local stimulation of antigen presenting cells such as dendritic cells responding to apoptotic/necrotic tumor cells.

Targeted modification of tumor microenvironment using LPH NP may allow for tumor cell-specific intervention without the adverse effects and complications from the systemic alteration.

The principle of GDEPT involves the genetic modification of tumor cells to produce enzymes capable of metabolizing nontoxic prodrugs into potent cytotoxins.