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In order to go a step further in the investigation of the senescence process, we investigated the effects of nitrogen deficiency on modifications of tissue and cell structure occurring in oilseed rape during senescence.
The early stage of this whole joint pathology is mainly characterized by a catabolic, inflammatory environment and the "chondropenia": a loss of hyaline articular cartilage volume and biochemical, ultrastructural and mechanical properties modifications of tissue (Aydin et al. 2007; Speziali et al. 2015).
While conventional radiology and computed tomography extract information from the differential attenuation of X-photons due to density and to the mean atomic number in the body volume sampled, the background of palpation-based diagnosis lies in the relationship linking several diseases to the modifications of tissue stiffness that they induce.
The accumulation of AGEs in living organisms also contributes to functional modifications of tissue proteins, resulting in the progress of normal aging and the pathogenesis of age-related diseases, such as diabetes, cardiovascular diseases, and Alzheimer's disease [ 6- 8].
Up till now, it has been rather difficult to assess the pathophysiological relevance of the modifications of tissue fatty acid composition due to a lower n-3 PUFA intake.
The failing heart undergoes a series of changes, from electrophysiological alterations in ion channels, exchangers, and pumps to structural modifications of tissue properties, that provide the underlying basis for arrhythmias.
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It reviews the broad aims of surface modification of tissue engineering scaffolds.
Surface modification of tissue engineering scaffolds and substrates is required for improving the efficacy of stem cell therapy by generating physicochemical stimulation promoting proliferation and differentiation of stem cells.
In this paper, we show that surface modification of tissue culture polystyrene (TCPS) with chemically derivatized elastin-like polypeptides (ELPs) enables control over the in vitro morphology and liver-specific function of primary rat hepatocytes.
The present study has examined the efficacy of a polymer microarray platform to screen a library of polyurethanes for applications such as human skeletal progenitor cell isolation and surface modification of tissue engineering scaffolds to enhance skeletal cell growth and differentiation.
The molecular mechanism of taurine's or GABA's inhibition and the investigation of its neuroprotective effects in vivo may prove useful for limiting the increased chemical modification of tissue proteins and cells on oxidative stress.
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