Sentence examples for modifications of target from inspiring English sources

Further modifications of target compounds are present at C-5 position of the pyrimidine ring.

FOXP3 is known to both activate and repress target genes by epigenetically regulating histone modifications of target promoters.

In the presence of high Ca2+ levels, TG2 can act as a crosslinking enzyme, catalyzing several post-translational modifications of target proteins.

(4) Whether intra-nuclear localization, three-dimensional organization, or epigenetic modifications of target DNA element potentially affect the binding of engineered TALE and Cas9 gRNA warrants further investigations.

The single vector strategy allows diverse modifications of target proteins recombinantly coexpressed in E. coli with heterologous enzymes.

Additionally, it is expected that disruption of histone modifications of target genes by aberrant hormonal and intracellular signals will be involved in the pathogenesis of other endocrine and metabolic diseases.

Firstly, a double strand DNA was designed with 5′-SH modification of probe DNA and 5′-OH mofificatargetf target DNA.

These methods are also instrumental for modification of target genes including gene truncations, site-specific mutagenesis and domain swapping.

Being mobile, impurity atoms, vacancies and interstitials can recombine and/or precipitate in the form of stable complexes which leads to the modification of target material properties.

The most common way to transmit these signals is by covalent modification of target proteins within the signaling pathway, most often adding a phosphate group (phosphorylation) or removing a phosphate group.

The history of transgenesis is marked by milestones such as the development of cellular transdifferentiation, recombinant DNA, genetic modification of target cells, and finally, the generation of simpler genetically modified organisms (e.g. bacteria and mice).