Sentence examples for modifications of lymphocyte from inspiring English sources

We used flow cytometry to investigate modifications of lymphocyte subpopulations related to pulmonary cytomegalovirus infections in blood and BAL samples from a series of 13 lung transplant recipients.

The genetic modification of lymphocytes is an important topic in the emerging field of gene therapy.

Our results demonstrate that pulmonary CMV infection is associated with a significant increase in the total lymphocyte population in BAL samples, but with minor modifications of the various lymphocyte subpopulations and a significantly higher absolute number of B lymphocytes in blood samples.

These results are in line with the OC-induced modifications of human T lymphocytes [ 37].

Following this proof of principle, the first gene therapy trial aimed at the correction of an inborn disease was based on the genetic modification of T-lymphocytes for the treatment of adenosine deaminase (ADA) deficiency (Blaese et al, 1995).

Regardless of the vector used, genome modification entails the risk of lymphocyte transformation, and possibly even de novo tumor formation.

The blood beryllium lymphocyte proliferation test (BeLPT) is a modification of the standard lymphocyte proliferation test that is used to identify persons who may have chronic beryllium disease.

Prevention of lymphocyte apoptosis, through either genetic modification of the host or treatment with specific inhibitors, markedly improves survival in murine sepsis models.

Our data indicate that SART possesses immunomodulatory properties, inducing an in vivo modification of the B lymphocyte response and anti-inflammatory properties, which are partly due to a reduction in cell migration and are most likely due to an inhibition of the production of inflammatory mediators.

The biological results shown here indicate that SART possesses immunomodulatory properties that induce an in vivo modification of the B lymphocyte response, as well as anti-inflammatory properties, partly due to a reduction in cell migration and most likely due to an inhibition of inflammatory mediator production.

Modification of T cell PTKs may thus underlie the HIV-induced impairment of lymphocyte function and may potentially predict disease progression.