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Third, involving doctors in proper evaluation and modifications of essential drug list policy is necessary, especially in deciding which drugs are on the list.
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The latter proves useful for making high-frequency changes that alter only the target amino acid sequence and even allows modification of essential genes.
We also developed an improved method for modification of essential genes.
Homeostatic maintenance within the ER is imperative for proper manufacture and modification of essential proteins.
Genetic modification of essential genes is particularly challenging because the function of the gene must be maintained throughout the procedure.
Modification of essential genes is also problematic using the two-step procedure because the first step results in interruption of the target gene by the mutation cassette.
Modes are properties that exist only as modifications of the essential (principal) and the general attributes of a substance.
Androgen-dependent changes in neuronal function reflect a rise from classical AR-mediated changes in the expression of receptors and channels, from biochemical modifications of these essential proteins, and from direct allosteric modulation of their function.
Our data point towards a model for gene regulation in which not only are the post-translational modifications of histones essential for establishing gene expression patterns, but equivalent modifications in DNA-binding transcription factors are also an integral part of whatever 'code' underlies these patterns.
Drought results on the modification of the essential oil chemotype from γ-terpinene/phenyl-1,2 ethanediol in the control seeds to γ-terpinene/cuminaldehyde in stressed ones.
Specifically, covalent modification of the essential serine residue on AChE is of prime importance in MS analyses because this step initiates neurotoxic events.
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