Sentence examples for modifications of endogenous from inspiring English sources
While multiple strategies to enhance plant carbon fixation have been suggested, and partially implemented, most of them are restricted to relatively simple modifications of endogenous metabolism, i.e., "low hanging fruit".
To determine the cellular modifications of endogenous Nm23-H1 and -H2 by oxidative stress, cellular Nm23-H1 was co-purified with Nm23-H2 by immunoprecipitation using Nm23-H1 antibody (Figure 1A) and various PTMs were analyzed using nanoAcquity™ UPLC™/ESI/q-TOF tandem MS as described in methodology.
We have tried from an early phase of this research to detect interactions and modifications of endogenous proteins.
36 Besides modifications of endogenous steroid profiles, other anabolic androgenic steroids such as 19-nortestosterone (nandrolone) and boldenone could be produced by microorganisms in urine matrix.
4-HPR is a well-studied antitumor agent with a mechanism of action that has been linked to oxidative stress induction [ 2, 10, 11], as well as to modifications of endogenous sphingolipid (SL) levels [ 1, 8, 12, 13].
Deletions or modifications of endogenous genomic copies of the dynein heavy chain (DYN1) and Lis1 (PAC1) were done using PCR-based methods as previously described (Longtine et al., 1998), using the URA3/5FOA 'pop-in/pop-out' method (Guthrie and Fink, 1991).
Furthermore, pinpoint modification of endogenous plant genes is also an attractive method in molecular plant breeding.
Future CAR T cell therapies could benefit from combined modification of endogenous TCR genes, histocompatibility genes, and components of signalling pathways.
This review evaluates the evidence for acyl glucuronide-derived perturbation of homeostasis, particularly that which might result from the covalent modification of endogenous proteins and other macromolecules.
On the other hand, our data indicate that the beneficial effects exerted by WT-MSCs are associated with a reduction in plasma PTX3, as if improvement of lung injury preceded modification of endogenous PTX3 production.
In summary, though acyl glucuronide-derived covalent modification of endogenous macromolecules is well-defined, the work ahead needs to provide detailed links between such modification and its possible biological consequences.
