Sentence examples for modifications of central from inspiring English sources

This paper concentrates on the modifications of central safety and interlock system, discharge control system, and timing and synchronization system.

N-Methylations of both DNA and histones are chromatin modifications of central importance in (epi genetics.

These results imply that nociception-evoked cortical hyperexcitability may involve modification of central modulating system and does not specific to trigeminal nociception.

In the absence of a peripheral mechanism for cold allodynia, a modification of central processing of cold stimuli after nerve injury could underlie the emergence of cold hypersensitivity.

Effect modification of central and window AC.

Continuous and intense nociceptive input from the OA knee joint may drive central sensitization, which may arise from chronic nociceptor stimulation and subsequent modification of central pain-transmitting neurons, and may be clinically associated with NP qualities [ 1, 2].

Histone modifications are of central importance in the regulation of transcription. 1, 2 Whilst histone acetylation is in general transcriptionally activating, histone lysine methylation can be activating or inhibitory depending on factors including the site and type of modification.

This approach led us to design chemical modifications of the central pyrazole, which solved the poor kinase selectivity seen as a strong liability for the initial compound 1.

To further elaborate on soldier-specific modifications of the central nervous system, the authors undertook anatomical and histological examinations of the brains and SOGs of termites.

To establish whether PK9119 has any potential to be improved in these critical aspects, it will be essential to systematically explore chemical modifications of its central indole scaffold.

The proposed class of designs is a modification of the Central Composite Designs, in which the axial points of the traditional central composite design are replaced by some edge points of the hypercube that circumscribes the sphere of zero center and radius a.