Sentence examples for modifications may play from inspiring English sources

Since the discovery that epigenetic modifications may play important roles in tumorigenesis, this discipline has become an attractive area for design of chemotherapeutics.

Thus, lamins and variations in nucleosome composition and/or modifications may play a role in the non-random positioning of certain chromosome territories near the nuclear membrane.

Such chromatin modifications may play a key role in lineage specification [35] and a model involving "histone modification pulsing" has been suggested as a mechanism whereby individual pluripotent cells may acquire differential fates [36].

Although histone modifications may play a crucial role in the transcriptional regulation of MMP-1, the relationship between UV-induced DNA damage and histone modification is not completely understood.

Although histone modifications may play a crucial role in the transcriptional regulation of MMP-1, the relationship between UV-induced histone modification and MMP-1 expression is not completely understood.

Post-translational modification events, such as glycosylation of the extracellular domains of both receptor and ligands also play an important role in Notch-ligand interactions [23], [24], and such modifications may play a part in tissue-specific responses to various ligands [25].

Recent studies indicate that chromatin modification may play a role in the regulation of FT expression.

However, translational controlling and modification may play roles in differential expression of versican V1 protein in these 4 cell lines.

The alteration in LOS structure seen in the commensal organisms suggests that the third heptose modification may play an important role in modulation LOS/LPS mediated toxicity.

To investigate whether such modification may play a role in the misfolding process we have studied the impact of methionine oxidation on the dynamics and energetics of the HuPrP(125 229) α-fold.

Taken together, these results suggest that chromatin modification may play a crucial role in CR-induced in vitro longevity, at least partly due to epigenetic p16 repression and that this occurs in all of the cell lines we examined.