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Given the exposure of the N-terminal region of histones to enzymatic modifications, it points to a possible differential utilization of the same lysine residues for different modifications.
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In addition, it points to modifications of Tfh effector molecules or Tfh subset balance as future therapeutic targets in RA.
Salted-PIN requires modifications to service points (e.g., ATM, point-of-sale), issuer/verification facilities, and bank cards; however, changes to intermediate switches are not required.
However, the methods [16] and [17] could not be directly applied to singular elliptic problems, and they required suitable modifications at the points of singularity.
Or perhaps a modification: 3 points for a win, 1 for a draw, 1 point for each goal scored up to 3; or leave the current scheme largely in tack but award no points for ties.
These structures present a potential to realize a spectrum of moduli with minimal modifications, a point of relevance for manufactures and designers.
Landscape attributes most frequently retained in step-wise regression models for each water quality parameter were agricultural chemical factors, followed by shoreline modifications and point source attributes.
Powder X-ray diffraction data coupled with differential scanning calorimetry and radioluminescence measurements were used to investigate structural modifications, melting point dependence and spectral emission dependence on the bromine/iodine ratio.
Here, we discuss the use of protein engineering methods (phage display and structure-based design) to develop novel mAbs, in some cases with exquisite specificity for particular target structural conformations, posttranslation modifications, or point mutations.
Cancer cells exhibit a wide range of genetic modifications, from point mutations to massive chromosomal aberrations (Stephens et al. 2011).
This mode of genesis implies the presence of a pre-existing MS and subsequent modifications by point mutation and slippage events.
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