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The expression pattern of tubulin isotypes, in addition to isotype-specific post-translational modifications, is thought to be critical for the morphogenesis of axons and dendrites.
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These surface modifications are thought to be useful for silicon band-gap engineering in the area of optoelectronics.
Epigenetic modifications are thought to play a key role in learning and forming memories, but this has not been very well explored because there are no good ways to disrupt the modifications, short of blocking histone modification of the entire genome.
These post-translational modifications are thought to act as markers that recruit proteins to specific regions of chromatin [3].
Reversible modifications are thought to be relevant in physiological processes, while non-reversible modifications may contribute to pathological situations and diseases [1].
Additional feedback loops and posttranslational modifications are thought to confer the 24 h period of this mechanism and to render it more robust.
Besides stabilization and activation, several post-translational modifications are thought to play a role in target gene selectivity [3], [4], [10].
Chromatin modifications are thought to regulate functional kinetochore assembly and maintenance by an epigenetic mechanism.
Combinations of modifications are thought to constitute the so-called "histone code".
These histone modifications are thought to be representative markers of active chromatin.
These modifications are thought to optimize rRNA folding, stability and function.
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