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Hence, technical improvements with regard to column design and tubing modifications is an important aspect to enhance mixing and mass transfer.
The ability to distinguish between forms of the same protein with differing post-translational modifications is an important advantage of aptamers as tools for identification and detection of biomarkers.
Therefore, the established lexicon of 'activating' and 'repressive' chromatin modifications is an over-simplification that should be curtailed.
Chromatin remodeling mediated by histone modifications is an important mechanism for specific gene expression (Ha et al., 2011).
In the latter case, the outcome of both genetic and epigenetic modifications is an aberrant overexpression and/or silencing of genes implicated in cell proliferation and/or in the control of cell death.
Extending these approaches to other post-translational modifications is an area of intense research, and a number of such PTM site prediction programs currently exist, although linking the PTM sites to the modifying enzymes remains to be addressed for the other types of modifications.
Similar(54)
Still, pushing loan modifications is a Congressional priority.
" 'Modifications' is a word greeted with caution by some insurers," says Ian Crowder of the AA.
But Mr. Ivanov said today that "compliance with the ABM treaty in its present form without any modifications is a prerequisite for further negotiations on nuclear disarmament".
(The desirability of deliberately making such modifications is a separate issue).
However, a poor compliance to lifestyle modifications is a daily reality.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com