Sentence examples for modifications involve heritable from inspiring English sources
Epigenetic modifications involve heritable changes in gene expression without changes in the nucleotide sequence [ 25– 27] and can include histone modification, DNA methylation, chromatin remodeling, or microRNA or prion activity [ 28– 30].
Epigenetic regulation involves heritable modifications that do not change the DNA sequences but provide "extra" layers of control to regulate chromatin organization and gene expression [12].
Epigenetic diversity involves heritable changes that affect genomic expression but that do not affect the DNA information.
His vehicle is a stainless-steel DeLorean with some major modifications involving plutonium.
Transformation: a heritable change involving an alteration in the genotype, usually subsequent to immortalisation.
Two levels of epigenetic gene regulation can now be envisaged: the classic form involving stable heritable changes and enhanced epigenetic modifications, which can be regarded as regulatory mechanisms orchestrating inducible responses at the cellular level which may or may not be heritable.
Interpretation of genetic information coded within the DNA is regulated by mechanisms that involve stable and heritable modifications of DNA and histones.
In this way, the geneticist can offer conclusive evidence for the presence of a locus involved in heritable trait variation.
The polycomb group (PcG) proteins and the DNA methylation systems are intimately involved in heritable repression of gene activity.
Most interestingly from a human health perspective, archaebacterial genes are less likely to be involved in heritable human disease.
As reported earlier by us and other groups, transcriptional gene silencing (TGS) does not require continuous presence of the effector siRNA/shRNA molecule and is heritable, involving epigenetic modifications, leading to long term transcriptional repression.
