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Epigenetic factors, such as DNA or histone modifications, are indispensable for precise gene expression in diverse immune cell types.
G protein γ-subunits are isoprenylated and carboxyl methylated at the C-terminal cysteine residue, and the set of the posttranslational modifications is indispensable for the function of the photoreceptor G protein transducin (Tα/Tβγ).
However, mice offer the opportunity for genetic modification and therefore are indispensable for future research in portal hypertension, despite the drawbacks described elsewhere [ 151, 152, 155].
The carbonizing process is also used (with slight modifications) to produce metallurgical coke, indispensable for the manufacture of iron and hence steel.
This example shows that modification using the effective DoF was indispensable for the NIRS SPM analysis to avoid over-estimation in statistical computation.
Prior preoperative adjustment is important and indispensable for MIS.
In particular, the PE head group including the primary amine at the ethanolamine moiety is indispensable for the recognition of PE by Ro09-0198, and chemical modifications of the primary amine abolish completely the recognition (47).
The 5-hydroxyl modification of raltegravir derivatives significantly increased the anti-HIV activity, which indicates that the hydroxyl may not be indispensable for raltegravir.
Although diet control and life style modification remain the first steps in obesity management [8], [9], the use of pharmaceutical agents may sometimes be indispensable for long-term treatment of obesity [10].
All mentioned phases are indispensable for the repair process; the second and third phase seem to be particularly important for the modification of the process in question [ 36].
Ferries are indispensable for transportation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com