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We therefore devised an experimental set-up to study Mdm2-dependent p53 post-translational modifications in yeast.
Some blocking mechanism(s) might strictly restrain the distribution of histone modifications in yeast.
Surprisingly, the codon-specific ribosome pausing we detected upon loss of U34 modifications in yeast was not augmented by environmental stresses.
Thank you for sending your work entitled " In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse" for consideration at eLife.
More recently, we quantitatively compared changes in the complete set of tRNA modifications in yeast exposed to four different oxidizing agents and five different alkylating agents.
GC- and AT-rich sequences have been shown to differ in chromatin conformation as well as histone modifications in yeast [ 52], which further strengthens the link between sequence and histone modifications.
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Sirtuins are known as regulators of age-dependent gene transcription and chromatin modification in yeast and in animals, but information about their occurrence and role in plants is scarce.
Besides the importance of PCNA modification in DDT, 9-1-1 modification in yeast seems to play a role in DNA damage management as well [27].
SUMO modification in yeast is catalyzed by a three-step enzyme reaction, involving the heterodimeric activating enzyme (E1) Uba2/Aos1, the conjugating enzyme (E2) Ubc9, and a few ligases (E3).
Trm11p is required for mG modification in yeast tRNA.
Tan1p is responsible for acC modification in yeast [ 42] and one Arabidopsis TAN1 homolog was found.
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