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Modifications in the use of promoters, the use of recombination regions, and the change in the order of the chains, are some of the genetic engineering changes that can increase the production of recombinant antibodies.
In view of the relatively long transfer times and the complexity of the remobilization processes of solutes, the expected effects of any modifications in the use of fertilizers, or of changes in pesticide-use legislation, would take a long time to become apparent.
24 Our study indicates a 0.9 g/day reduction in population dietary salt intake between surveys, which should be interpreted as primarily deriving from food reformulation rather than by behavioural modifications in the use of discretionary salt at the table and in cooking.
4. To describe modifications in the use of health services by the dependent's family caregivers who received the benefits of the LPAPAD. 5. To compare the results achieved (mental health, overburden, quality of life and use of health services) in those family caregivers, according to the type of benefits chosen.
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Accordingly, no significant modification in the use of chemotherapy for resectable disease was to be expected.
Our findings suggest that a modification in the use of the current CellSearch system can result in a significant increase in the ability to isolate and characterise CTCs from patients with breast cancer and NSCLC.
The results of different studies revealed that all stages have relevant environmental impacts like topsoil loss, change in the use of land, modification of natural drainage and groundwater patterns, landslides, erosion, sedimentation, landscape degradation, increase in noise and dust levels, fuel and oil spills, waste generation, and air, soil and water pollution.
The new modification resulted in the use of smaller amount of nitrogen, higher cutting speeds at heavy depth of cuts and better surface finish.
In a May 2005 order, the Trial Chamber made some modifications to the use of time in the defence case (Prosecutor v. Milošević 19 May 2005).
Different elements of the intervention included training of ADL, home modifications, supply of and supervision in the use of adaptive equipment for use during hospitalisation and at home, assisting the patient in prioritising between ADL and instruction in self-training programmes and transfers (accessibility and mobility in the home environment) (Table 1).
In 2007 Capecchi, Evans and Smithies received the Nobel Prize 'for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells'; they used homologous recombination in embryonic stem cells [ 66].
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