Sentence examples for modifications in the development of from inspiring English sources
The major impacts of genetic modifications in the development of infectious diseases or on the contrary in their eradication are analyzed in this article.
These studies have suggested the role of histone modifications in the development of diabetic retinopathy [ 66].
Therefore, the impact of epigenetic modifications in the development of rheumatoid diseases will be exemplified by discussing epigenetic changes in RA by focusing on RA synovial fibroblasts (RASFs).
In this review we consider the role of diverse epigenetic modifications in the development of RA, with a special focus on epigenetic modifications in RASF.
In this review we draw a detailed picture for the role of diverse epigenetic modifications in the development of RA with a special focus on epigenetic modifications in RASF.
These findings demonstrate the critical role of histone modifications in the development of fibroblast resistance to apoptosis in both a murine model and in patients with pulmonary fibrosis and suggest novel approaches to therapy for progressive fibroproliferative disorders.
Compounds 6a and 6c represent a new structure type for reductive activation and a lead for further modification in the development of better analogues with improved selective toxicity to be used in gene-directed enzyme prodrug therapy.
We have previously reported that ∼25% of human subjects with the sporadic idiopathic interstitial pneumonias have short telomere lengths (<10th percentile) in the absence of telomerase mutations[19], suggesting a role of this epigenetic modification in the development of non-familial pulmonary fibrosis.
Significant difference in methylation levels of a number of genes distinguished tumour tissue samples from their matched normal, demonstrating epigenetic modifications acquired in the development of tumours.
It is likely that epigenetic processes including changes in histone modifications affect the development of germ cell tumours.
9 11 34 Presentation of the evolving intervention to a Stakeholder Advisory Group resulted in important modifications, including the development of the agenda setting tool.
