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Overall, our results suggest that modifications in survival and growth rates alter the life-history strategies of these fish at the cost of their reproductive success.
Based on the overlapping functions of the three histone methylation marks, we hypothesized that combining these three modifications in survival analyses would be more informative than the individual markers with respect to patient survival and tumor recurrence.
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5 6 Refinements in primary operative techniques had not made a difference 7 and it was considered unlikely that technical modifications would lead to improvement in survival following surgery.
Stem cells have a greater propensity to accumulate genetic and epigenetic modifications in order to acquire a survival advantage when under selection pressure [ 12].
We did not observe a significant effect of modification by any of the covariates in survival analysis (all p interaction >0.25).
Other treatment modifications were not associated with significant decrease in survival after adjusting for potential confounders.
No significant effect modification was observed by any of the covariates in survival analysis (all p interaction >0.25).
With present technologies and strategies for radioprotection of normal structures, improvements in survival are unlikely to result from modifications in total dose or fraction size.
Extreme mortalities were observed in the younger class of oysters, while the modification of growing height led to a significant increase in survival of adult oysters.
"Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC". Clinical Epigenetics 10 (1): 41. doi 10.1186/s13148-018-0474-3. http://dx.doi.org/10.1186/s13148-018-0474-3. Backgroundemethylasene demethylase family members are related to lung cancer clinical outcomes and are potential biomarkers for chemotherapeutics.
Germ-line dependent epigenetics, on the other hand, are mediated by meiotic and embryonic survival of epigenetic modifications in germ cells, like DNA-methylation or variations in chromatin structure [32].
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