Sentence examples for modifications in specific from inspiring English sources
Interestingly, epigenetic modifications in specific brain regions have been shown to be associated with the neurobiology of psychiatric disorders, including alcoholism and stress.
It has been known that changes in H3K9Ac and H3K9Me2 modifications can influence the chromatin structure and affect gene expression [31], and these epigenetic modifications in specific loci could be critical for determining the fate of stem cells [20].
It will be important to investigate various cytosine and histone modifications in specific brain cell types to understand their potential roles in the pathophysiology of schizophrenia.
By a visual comparative analysis of the spectra, it is possible to see, over time, gradual spectral changes of the overall profile with consistent modifications in specific spectral regions.
The complexity can be simplified by concentrating on wobble base modifications in specific tRNAs and then analyzing patterns of codon usage in specific transcripts, but an appreciation of the degeneracy of the genetic code is required to move the model to the next level.
These definitions of positive and negative results are in accordance with the published literature (Goldstein and Armin, 2001) but may require modification in specific context.
Bivalent modifications resolve in specific lineages but may remain in parallel differentiated lineages, depending on the relative distance of the cell types.
Importantly, the combination of different modifications results in specific transcriptional or structural outcomes, underlining the existence of a "histone code" [ 9, 10].
These mutants were obtained through evolutionary modifications in two specific regions of the CPMO's putative active site.
Peculiarities in the spatial distribution of the cavity sizes persist for larger separations from the nanoparticle than modifications in the specific volume.
In order to investigate the significance of histone modification changes in specific regions of Sox2, Oct4 and β-globin in transplanted nuclei, we have conducted ChIP analysis.
