Sentence examples for modifications in sequence from inspiring English sources

During evolution, protein domains undergo many modifications in sequence and structure to achieve versatility in function.

These results suggest that the basic MDP structure easily accommodates modifications in sequence and, for SHED cells, the threonine-containing gels require the integrin-binding RGDS sequence for cell attachment to occur, while the serine-based gels are less selective and support an increase in cell number, regardless of the presence or absence of RGDS.

In the first step, the exact position of the modifications in the sequence was established by an adopted version of the phosphoRS algorithm [ 40].

For MLST, seven housekeeping genes were amplified using the method described by Bartual et al., [ 14] with some modifications in the sequence of gyrB and rpoD primers as given by Park et al. [ 15].

These duplicated paralogs could obtain partial and/or novel functions or exert dosage effects, acquire novel regulatory elements for tissue-specific expression, possess modifications in seed sequence resulting in novel microRNAs, and potentially beneficial or detrimental to certain individuals or a specific population [ 29].

An additional cause for the results may also be the fact that many species are closely related in the targeted 16S mtDNA region, and as such small modifications in the sequences due to DNA damage, heteroplasmy, or PCR enzyme error might lead to erroneous sequence identification.

Modifications in regulatory sequences allowing unique expression patterns, addition of new domains, and modifying the amino acid sequence of the DCX domains themselves explains – at least in part- why this superfamily is thriving.

For all the conserved miRNA families, single-nucleotide modifications in the sequences were analysed in detail based on the data presented in [ 30].

Therefore the stability of N. equitans proteins in extremely high temperatures is apparently provided by significant modifications in their sequences toward enrichment of certain residues.

Accurately identifying modifications in protein sequences is a critical first step for PTM profiling, and thus our approach may benefit routine proteomic analysis.

Accurate identification of protein modifications in protein sequences is a critical first step in any PTM study, and thus it may benefit the utility of proteomic profiling to address research problems in basic biology, as well as biomarker discovery and drug development in the clinical domain.