Sentence examples for modifications in miRNAs from inspiring English sources

This similarity suggests common base modifications in miRNAs and tRNAs, although the nature of base modifications in miRNAs can only be determined experimentally in the future.

Next, we investigated potential RNA base modifications in miRNAs.

Our bioinformatics analysis strongly suggested RNA base modifications in miRNAs.

After describing base modifications in tRNAs, we next considered possible base modifications in miRNAs.

What would be the biological effects of base modifications in miRNAs?

Our analysis suggests that base modifications in miRNAs may prevent the maturation of miRNAs, although it is also possible that some base modifications in miRNAs may inhibit or enhance the targeting of miRNAs.

We then verified whether the observed modifications in miRNA expression are specific for islet cells.

In addition, the lavages of the patient with ADH differed in the relative abundance of other miRNAs when compared to the lavages with less severe epithelial atypia (Figure 6C), perhaps indicating that different cellular changes induce different modifications in the miRNA composition of ductal lavages.

All those data suggest that end modifications in mature miRNA could unlikely be a processing error.

In addition to differences in protein-coding genes, the islets of 12-month-old rats also displayed modifications in the miRNA profile.

Nonetheless, our method achieves accurate inference of miRNA activity modification in the miRNA transfection data as shown above.