Sentence examples for modifications in human from inspiring English sources

The recent development of monoclonal antibodies against phospho-histidine has redefined our view of such modifications in human cells (Fuhs et al., 2015).

Modifications in human Cx40 with designed variants (D55N or P193Q, but not P193K) are sufficient to establish morphological and functional heterotypic GJs with Cx45.

We previously proposed the utility of IN mutant lentiviral vectors that are selectively activated by complementary LEDGF/p75 variants, and our initial modifications in human immunodeficiency virus type 1 IN and LEDGF/p75 supported about 13% of wild-type vector transduction activity.

To analyze histones and their modifications in human adipocytes we isolated adipocytes from abdominal subcutaneous fat tissue of female subjects, obtained during elective surgery.

Currently there is only one high-resolution genome-scale profiling about histone modifications in human, which detected 20 histone methylations in T cells[32].

The regulation of epigenetic modifications in human pre-implantation embryos needs to be explored in further depth in order to understand the underlying molecular mechanisms behind early human development as well as the low efficiency of parthenogenesis and SCNT.

Does BAIBA produce similar modifications in humans?

Investigating these modifications in humans could shed light on so far unknown mechanisms of aging.

Histones and their modifications in humans (mammals) are partially addressed in Human Histone Modification Database (HHMD) (40), Histone Database (41) and HIstome (42).

Similarly, additional emerging factors that recognize these modifications in humans can be tested (e.g., Spartan [35,36], ZRANB3 [37 39], and PARI [15]).

In conclusion, the now standardized technologies of epigenome analysis coupled with whole-genome expression studies are required to determine the biological and clinical impact of environmentally induced epigenetic modifications in humans.