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Landscape modifications in combination with a highly intensive agriculture are known to have negative impacts on farmland biodiversity.
These modifications, in combination with elucidation of the mechanism of action of ASOs and improved clinical trial design, have provided momentum for the translation of ASO-based strategies into therapies.
This platform, termed ID-VP02, utilizes a novel genetic variant of a Sindbis virus envelope glycoprotein with posttranslational carbohydrate modifications in combination with Vpx, a SIVmac viral accessory protein, to achieve efficient targeting and transduction of human DCs.
Cumulative drainage of the six lysimeter soils ranged from 57 for the least to 104 mm y−1 for the most eroded Luvisols; the differences of about 83% indicated that the erosional profile modifications in combination with differences in crop development affected the water balance components.
These modifications in combination fit into the theme that the PTO is forcing inventors to document a clearer path for examiners in the filing process in an attempt to clean up the heavy volume of patents being ramped in.
These modifications, in combination with reactive oxygen species (ROS), may generate DNA single or double-strand breaks, which in turn may lead to mutations, chromosomal aberrations, and microsatellite instability [6][7].
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Using mice with specific genetic modifications in suspected vulnerability genes in combination with CMS as environmental factor will allow scrutinising the role of both, the candidate gene and stress in a genetically predisposed animal, as risk factors for depression.
This modification in combination with the extension of the reduction zone, will allow, to increases the efficiency of the tar thermal cracking inside the gasifier and the extension of the Boudouard reactions.
Kinase modification in combination with the addition of PEG has increased ligation-mediated PCR amplification over 20-fold, enabling >400-fold amplification of starting DNA.
The most studied histone modifications are histone acetylation/deacetylation, and more recently methylation/demethylation. In breast cancer, abnormal histone modification in combination with DNA hypermethylation is frequently associated with epigenetic silencing of tumor suppressor genes and genomic instability [ 2, 3].
Both ADA and AACE/ACE recommend lifestyle modification in combination with antidiabetes monotherapy at the time of diagnosis (28, 38, 39), with persistent monitoring every 2 3 months until glycemic goals are achieved.
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change in combination
alteration in combination
modifications in gene
modifications in Section
modifications in turn
modifications in elp
modifications in practice
modifications in research
modifications in method
modifications in design
modifications in plant
modifications in actin
modifications in chromatin
modifications in place
modifications in fact
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